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authorId(s): 12401407
Author(s): Laksshman Sundaram
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330
Predicting the clinical impact of human mutation with deep neural networks
Laksshman Sundaram
,
Hong Gao
, ...,
K. Farh
2018
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241
Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution
Alexandro E. Trevino
,
Fabian Müller
, ...,
W. Greenleaf
2020
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67
The landscape of tolerated genetic variation in humans and primates
Hong Gao
,
T. Hamp
, ...,
K. Farh
2023
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43
DeepBipolar: Identifying genomic mutations for bipolar disorder via deep learning
Laksshman Sundaram
,
R. R. Bhat
, ...,
Xiaolin Li
2017
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40
Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges
Roxana Daneshjou
,
Yanran Wang
, ...,
Alexander A. Morgan
2017
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34
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease
M. Ameen
,
Laksshman Sundaram
, ...,
A. Kundaje
2022
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20
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
Shantanu Constantina Steven E. Predrag John Susanna Roger A Jain Bakolitsa Brenner Radivojac Moult Repo Hoskin
,
Shantanu Jain
, ...,
J. Zook
2022
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18
Identification of constrained sequence elements across 239 primate genomes
Lukas F. K. Kuderna
,
Jacob C. Ulirsch
, ...,
K. Farh
2023
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7
Stepwise Generation of Human Induced Pluripotent Stem Cell-Derived Cardiac Pericytes to Model Coronary Microvascular Dysfunction.
Mengcheng Shen
,
Chun Liu
, ...,
Joseph C. Wu
2023
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7
Transcription factor stoichiometry, motif affinity and syntax regulate single-cell chromatin dynamics during fibroblast reprogramming to pluripotency
Surag Nair
,
Mohamed Ameen
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A. Kundaje
2023
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