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authorId(s): 12401407
Author(s): Laksshman Sundaram
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330
Predicting the clinical impact of human mutation with deep neural networks
Laksshman Sundaram, Hong Gao, ..., K. Farh
2018
241
Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution
Alexandro E. Trevino, Fabian Müller, ..., W. Greenleaf
2020
67
The landscape of tolerated genetic variation in humans and primates
Hong Gao, T. Hamp, ..., K. Farh
2023
43
DeepBipolar: Identifying genomic mutations for bipolar disorder via deep learning
Laksshman Sundaram, R. R. Bhat, ..., Xiaolin Li
2017
40
Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges
Roxana Daneshjou, Yanran Wang, ..., Alexander A. Morgan
2017
34
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease
M. Ameen, Laksshman Sundaram, ..., A. Kundaje
2022
20
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
Shantanu Constantina Steven E. Predrag John Susanna Roger A Jain Bakolitsa Brenner Radivojac Moult Repo Hoskin, Shantanu Jain, ..., J. Zook
2022
18
Identification of constrained sequence elements across 239 primate genomes
Lukas F. K. Kuderna, Jacob C. Ulirsch, ..., K. Farh
2023
7
Stepwise Generation of Human Induced Pluripotent Stem Cell-Derived Cardiac Pericytes to Model Coronary Microvascular Dysfunction.
Mengcheng Shen, Chun Liu, ..., Joseph C. Wu
2023
7
Transcription factor stoichiometry, motif affinity and syntax regulate single-cell chromatin dynamics during fibroblast reprogramming to pluripotency
Surag Nair, Mohamed Ameen, ..., A. Kundaje
2023

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